DnaJ homolog subfamily C member 4 (DNAJC4)

About DnaJ homolog subfamily C member 4

DnaJ homolog subfamily C member 4 (DNAJC4) is a protein from Homo sapiens identified by UniProt accession Q9NNZ3, 241 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.

Target properties

Protein name	DnaJ homolog subfamily C member 4
UniProt accession	Q9NNZ3
Gene	DNAJC4
Organism	Homo sapiens
Length	241 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (31)

Diseases linked to this target (Open Targets).

mean corpuscular volume · score 0.05
diet measurement · score 0.05
platelet count · score 0.04
monocyte percentage of leukocytes · score 0.03
serum alanine aminotransferase measurement · score 0.03
mean reticulocyte volume · score 0.03
body mass index · score 0.03
reticulocyte count · score 0.03
bipolar disorder · score 0.02
cognitive function measurement · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NNZ3-F1	alphafold	PREDICTED	77.41	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NNZ3.

Amino-acid sequence (241 residues)

MPPLLPLRLC RLWPRNPPSR LLGAAAGQRS RPSTYYELLG VHPGASTEEV KRAFFSKSKE LHPDRDPGNP SLHSRFVELS EAYRVLSREQ SRRSYDDQLR SGSPPKSPRT TVHDKSAHQT HSSWTPPNAQ YWSQFHSVRP QGPQLRQQQH KQNKQVLGYC LLLMLAGMGL HYIAFRKVKQ MHLNFMDEKD RIITAFYNEA RARARANRGI LQQERQRLGQ RQPPPSEPTQ GPEIVPRGAG P

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards