Protamine-3 (PRM3)
Homo sapiens — UniProt Q9NNZ6
Data last refreshed: (UniProt release unknown)
Key facts
Protamine-3 (PRM3) is a protein from Homo sapiens identified by UniProt accession Q9NNZ6, 103 residues long. MolForge cross-references it against 0 known binders and 99 disease associations.
- UniProt accession: Q9NNZ6; gene symbol PRM3.
- Organism: Homo sapiens.
- Length: 103 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, drug dependence and azoospermia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protamine-3 |
|---|---|
| UniProt accession | Q9NNZ6 |
| Gene | PRM3 |
| Organism | Homo sapiens |
| Length | 103 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (99)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.23
- drug dependence · score 0.08
- azoospermia · score 0.07
- eosinophil count · score 0.07
- male infertility with teratozoospermia due to single gene mutation · score 0.07
- Hepatitis · score 0.07
- mean corpuscular volume · score 0.06
- spermatogenic failure 55 · score 0.06
- spermatogenic failure 3 · score 0.06
- gut microbiome measurement · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NNZ6-F1 | alphafold | PREDICTED | 57.89 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NNZ6.
Amino-acid sequence (103 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PRM3?
The strongest Open Targets associations for PRM3 are neurodegenerative disease, drug dependence, azoospermia, eosinophil count and male infertility with teratozoospermia due to single gene mutation.
How long is the PRM3 protein?
The Homo sapiens PRM3 protein (UniProt Q9NNZ6) is 103 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NNZ6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NNZ6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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