Large ribosomal subunit protein mL65 (MRPS30)
Homo sapiens — UniProt Q9NP92
Data last refreshed: (UniProt release unknown)
Key facts
Large ribosomal subunit protein mL65 (MRPS30) is a protein from Homo sapiens identified by UniProt accession Q9NP92, 439 residues long. MolForge cross-references it against 0 known binders and 53 disease associations.
- UniProt accession: Q9NP92; gene symbol MRPS30.
- Organism: Homo sapiens.
- Length: 439 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, breast carcinoma and creatinine measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Large ribosomal subunit protein mL65 |
|---|---|
| UniProt accession | Q9NP92 |
| Gene | MRPS30 |
| Organism | Homo sapiens |
| Length | 439 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (53)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.46
- breast carcinoma · score 0.33
- creatinine measurement · score 0.31
- breast cancer · score 0.28
- type 2 diabetes mellitus · score 0.28
- HER2 Positive Breast Carcinoma · score 0.26
- schizophrenia · score 0.24
- electrocardiography · score 0.24
- glomerular filtration rate · score 0.22
- HER2 negative breast carcinoma · score 0.21
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NP92-F1 | alphafold | PREDICTED | 87.65 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NP92.
Amino-acid sequence (439 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MRPS30?
The strongest Open Targets associations for MRPS30 are neurodegenerative disease, breast carcinoma, creatinine measurement, breast cancer and type 2 diabetes mellitus.
How long is the MRPS30 protein?
The Homo sapiens MRPS30 protein (UniProt Q9NP92) is 439 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NP92 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NP92 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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