Calcium-activated potassium channel subunit beta-3 (KCNMB3)
Homo sapiens — UniProt Q9NPA1
Data last refreshed: (UniProt release unknown)
Key facts
Calcium-activated potassium channel subunit beta-3 (KCNMB3) is a protein from Homo sapiens identified by UniProt accession Q9NPA1, 279 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.
- UniProt accession: Q9NPA1; gene symbol KCNMB3.
- Organism: Homo sapiens.
- Length: 279 amino acids.
- Top disease associations (Open Targets): mean corpuscular hemoglobin, insulin like growth factor measurement and drug use measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Calcium-activated potassium channel subunit beta-3 |
|---|---|
| UniProt accession | Q9NPA1 |
| Gene | KCNMB3 |
| Organism | Homo sapiens |
| Length | 279 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (15)
Diseases linked to this target (Open Targets).
- mean corpuscular hemoglobin · score 0.11
- insulin like growth factor measurement · score 0.09
- drug use measurement · score 0.08
- metabolite measurement · score 0.08
- insulin resistance · score 0.05
- mean corpuscular hemoglobin concentration · score 0.03
- body height · score 0.02
- erythrocyte count · score 0.02
- Insulin resistance · score 0.01
- squamous cell carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NPA1-F1 | alphafold | PREDICTED | 72.07 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NPA1.
Amino-acid sequence (279 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KCNMB3?
The strongest Open Targets associations for KCNMB3 are mean corpuscular hemoglobin, insulin like growth factor measurement, drug use measurement, metabolite measurement and insulin resistance.
How long is the KCNMB3 protein?
The Homo sapiens KCNMB3 protein (UniProt Q9NPA1) is 279 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NPA1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NPA1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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