Neuroglobin (NGB)
Homo sapiens — UniProt Q9NPG2
Data last refreshed: (UniProt release unknown)
Key facts
Neuroglobin (NGB) is a protein from Homo sapiens identified by UniProt accession Q9NPG2, 151 residues long. MolForge cross-references it against 0 known binders and 120 disease associations.
- UniProt accession: Q9NPG2; gene symbol NGB.
- Organism: Homo sapiens.
- Length: 151 amino acids.
- Top disease associations (Open Targets): neuroinflammatory disorder, protein measurement and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Neuroglobin |
|---|---|
| UniProt accession | Q9NPG2 |
| Gene | NGB |
| Organism | Homo sapiens |
| Length | 151 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (120)
Diseases linked to this target (Open Targets).
- neuroinflammatory disorder · score 0.28
- protein measurement · score 0.12
- neoplasm · score 0.09
- mathematical ability · score 0.09
- Stroke · score 0.08
- cancer · score 0.08
- colorectal carcinoma · score 0.07
- breast cancer · score 0.06
- Spinal cord injury · score 0.05
- neuroblastoma · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NPG2-F1 | alphafold | PREDICTED | 95.16 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NPG2.
Amino-acid sequence (151 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NGB?
The strongest Open Targets associations for NGB are neuroinflammatory disorder, protein measurement, neoplasm, mathematical ability and Stroke.
How long is the NGB protein?
The Homo sapiens NGB protein (UniProt Q9NPG2) is 151 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NPG2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NPG2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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