Ubinuclein-1 (UBN1)
Homo sapiens — UniProt Q9NPG3
Data last refreshed: (UniProt release unknown)
Key facts
Ubinuclein-1 (UBN1) is a protein from Homo sapiens identified by UniProt accession Q9NPG3, 1134 residues long. MolForge cross-references it against 0 known binders and 82 disease associations.
- UniProt accession: Q9NPG3; gene symbol UBN1.
- Organism: Homo sapiens.
- Length: 1134 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, Non-immune hydrops fetalis and breast adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ubinuclein-1 |
|---|---|
| UniProt accession | Q9NPG3 |
| Gene | UBN1 |
| Organism | Homo sapiens |
| Length | 1134 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (82)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.32
- Non-immune hydrops fetalis · score 0.27
- breast adenocarcinoma · score 0.26
- glioblastoma multiforme · score 0.25
- squamous cell lung carcinoma · score 0.23
- gastric adenocarcinoma · score 0.23
- head and neck squamous cell carcinoma · score 0.23
- lung adenocarcinoma · score 0.23
- esophageal cancer · score 0.23
- endometrial cancer · score 0.23
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NPG3-F1 | alphafold | PREDICTED | 54.58 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NPG3.
Amino-acid sequence (1134 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with UBN1?
The strongest Open Targets associations for UBN1 are neurodegenerative disease, Non-immune hydrops fetalis, breast adenocarcinoma, glioblastoma multiforme and squamous cell lung carcinoma.
How long is the UBN1 protein?
The Homo sapiens UBN1 protein (UniProt Q9NPG3) is 1134 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NPG3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NPG3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.