Transcriptional repressor scratch 2 (SCRT2)
Homo sapiens — UniProt Q9NQ03
Data last refreshed: (UniProt release unknown)
Key facts
Transcriptional repressor scratch 2 (SCRT2) is a protein from Homo sapiens identified by UniProt accession Q9NQ03, 307 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.
- UniProt accession: Q9NQ03; gene symbol SCRT2.
- Organism: Homo sapiens.
- Length: 307 amino acids.
- Top disease associations (Open Targets): neurofibrillary tangles measurement, Recurrent aphthous stomatitis and helping behavior measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transcriptional repressor scratch 2 |
|---|---|
| UniProt accession | Q9NQ03 |
| Gene | SCRT2 |
| Organism | Homo sapiens |
| Length | 307 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (11)
Diseases linked to this target (Open Targets).
- neurofibrillary tangles measurement · score 0.16
- Recurrent aphthous stomatitis · score 0.09
- helping behavior measurement · score 0.04
- QRS duration · score 0.04
- birth weight · score 0.02
- autism · score 0.02
- breast carcinoma · score 0.01
- Ataxia-telangiectasia · score 0.01
- cardiovascular disease · score 0.00
- chronic kidney disease · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NQ03-F1 | alphafold | PREDICTED | 56.37 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQ03.
Amino-acid sequence (307 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SCRT2?
The strongest Open Targets associations for SCRT2 are neurofibrillary tangles measurement, Recurrent aphthous stomatitis, helping behavior measurement, QRS duration and birth weight.
How long is the SCRT2 protein?
The Homo sapiens SCRT2 protein (UniProt Q9NQ03) is 307 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NQ03 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NQ03 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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