SLAM family member 7 (SLAMF7)
Homo sapiens — UniProt Q9NQ25
Data last refreshed: (UniProt release unknown)
Key facts
SLAM family member 7 (SLAMF7) is a protein from Homo sapiens identified by UniProt accession Q9NQ25, 335 residues long. MolForge cross-references it against 1 known binders and 153 disease associations.
- UniProt accession: Q9NQ25; gene symbol SLAMF7.
- Organism: Homo sapiens.
- Length: 335 amino acids.
- Approved drugs acting on it (DrugCentral): Elotuzumab.
- Top disease associations (Open Targets): multiple myeloma, neoplasm and blood protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | SLAM family member 7 |
|---|---|
| UniProt accession | Q9NQ25 |
| Gene | SLAMF7 |
| Organism | Homo sapiens |
| Length | 335 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). Approved drug exists
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Approved drugs acting on this target (1)
Approved drugs whose DrugCentral mechanism of action is this protein, most potent first.
Disease associations (153)
Diseases linked to this target (Open Targets).
- multiple myeloma · score 0.57
- neoplasm · score 0.40
- blood protein measurement · score 0.36
- protein measurement · score 0.27
- SLAM family member 7 measurement · score 0.27
- serum IgM measurement · score 0.25
- multiple sclerosis · score 0.23
- acute myeloid leukemia · score 0.10
- Miyoshi myopathy · score 0.09
- IgG4-related disease · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NQ25-F1 | alphafold | PREDICTED | 78.21 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQ25.
Amino-acid sequence (335 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which approved drugs target SLAMF7?
DrugCentral lists 1 approved drug whose mechanism of action is SLAMF7: Elotuzumab.
Which diseases are associated with SLAMF7?
The strongest Open Targets associations for SLAMF7 are multiple myeloma, neoplasm, blood protein measurement, protein measurement and SLAM family member 7 measurement.
How long is the SLAMF7 protein?
The Homo sapiens SLAMF7 protein (UniProt Q9NQ25) is 335 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NQ25 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NQ25 — predicted 3D structure (CC BY 4.0)
- DrugCentral — approved drugs and mechanism-of-action links (CC BY-SA 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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