Putative RNA-binding protein Luc7-like 1 (LUC7L)
Homo sapiens — UniProt Q9NQ29
Data last refreshed: (UniProt release unknown)
Key facts
Putative RNA-binding protein Luc7-like 1 (LUC7L) is a protein from Homo sapiens identified by UniProt accession Q9NQ29, 371 residues long. MolForge cross-references it against 0 known binders and 76 disease associations.
- UniProt accession: Q9NQ29; gene symbol LUC7L.
- Organism: Homo sapiens.
- Length: 371 amino acids.
- Top disease associations (Open Targets): Alpha-thalassemia, reticulocyte count and mean corpuscular volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Putative RNA-binding protein Luc7-like 1 |
|---|---|
| UniProt accession | Q9NQ29 |
| Gene | LUC7L |
| Organism | Homo sapiens |
| Length | 371 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (76)
Diseases linked to this target (Open Targets).
- Alpha-thalassemia · score 0.33
- reticulocyte count · score 0.24
- mean corpuscular volume · score 0.24
- reticulocyte measurement · score 0.23
- mean corpuscular hemoglobin · score 0.22
- mean reticulocyte volume · score 0.21
- mean corpuscular hemoglobin concentration · score 0.17
- Red cell distribution width · score 0.17
- Immature Reticulocyte Fraction Measurement · score 0.13
- mental or behavioural disorder · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NQ29-F1 | alphafold | PREDICTED | 68.65 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQ29.
Amino-acid sequence (371 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LUC7L?
The strongest Open Targets associations for LUC7L are Alpha-thalassemia, reticulocyte count, mean corpuscular volume, reticulocyte measurement and mean corpuscular hemoglobin.
How long is the LUC7L protein?
The Homo sapiens LUC7L protein (UniProt Q9NQ29) is 371 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NQ29 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NQ29 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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