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A-kinase-interacting protein 1 (AKIP1)

Homo sapiens — UniProt Q9NQ31

Gene: AKIP1Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

A-kinase-interacting protein 1 (AKIP1) is a protein from Homo sapiens identified by UniProt accession Q9NQ31, 210 residues long. MolForge cross-references it against 0 known binders and 79 disease associations.

  • UniProt accession: Q9NQ31; gene symbol AKIP1.
  • Organism: Homo sapiens.
  • Length: 210 amino acids.
  • Top disease associations (Open Targets): alkaline phosphatase measurement, neuroimaging measurement and heel bone mineral density.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameA-kinase-interacting protein 1
UniProt accessionQ9NQ31
GeneAKIP1
OrganismHomo sapiens
Length210 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (79)

Diseases linked to this target (Open Targets).

  • alkaline phosphatase measurement · score 0.27
  • neuroimaging measurement · score 0.18
  • heel bone mineral density · score 0.17
  • Red cell distribution width · score 0.16
  • hemoglobin measurement · score 0.16
  • platelet count · score 0.15
  • brain volume measurement · score 0.15
  • bone quantitative ultrasound measurement · score 0.14
  • diastolic blood pressure · score 0.14
  • brain measurement · score 0.14

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9NQ31-F1alphafoldPREDICTED68.19—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQ31.

Amino-acid sequence (210 residues)

MDNCLAAAAL NGVDRRSLQR SARLALEVLE RAKRRAVDWH ALERPKGCMG VLAREAPHLE KQPAAGPQRV LPGEREERPP TLSASFRTMA EFMDYTSSQC GKYYSSVPEE GGATHVYRYH RGESKLHMCL DIGNGQRKDR KKTSLGPGGS YQISEHAPEA SQPAENISKD LYIEVYPGTY SVTVGSNDLT KKTHVVAVDS GQSVDLVFPV

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with AKIP1?

The strongest Open Targets associations for AKIP1 are alkaline phosphatase measurement, neuroimaging measurement, heel bone mineral density, Red cell distribution width and hemoglobin measurement.

How long is the AKIP1 protein?

The Homo sapiens AKIP1 protein (UniProt Q9NQ31) is 210 amino acids long.

Browse: Targets: A · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9NQ31
GeneAKIP1
OrganismHomo sapiens
Length210
Binders0
Diseases79
View on UniProt