Transmembrane protein 9B (TMEM9B)
Homo sapiens — UniProt Q9NQ34
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane protein 9B (TMEM9B) is a protein from Homo sapiens identified by UniProt accession Q9NQ34, 198 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.
- UniProt accession: Q9NQ34; gene symbol TMEM9B.
- Organism: Homo sapiens.
- Length: 198 amino acids.
- Top disease associations (Open Targets): BMI-adjusted waist-hip ratio, waist-hip ratio and hemoglobin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane protein 9B |
|---|---|
| UniProt accession | Q9NQ34 |
| Gene | TMEM9B |
| Organism | Homo sapiens |
| Length | 198 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (41)
Diseases linked to this target (Open Targets).
- BMI-adjusted waist-hip ratio · score 0.11
- waist-hip ratio · score 0.07
- hemoglobin measurement · score 0.06
- monocyte count · score 0.06
- neutrophil count · score 0.06
- cortical surface area measurement · score 0.05
- hematocrit · score 0.05
- FEV/FVC ratio · score 0.05
- cholesterol-ester transfer protein deficiency · score 0.04
- dehydrated hereditary stomatocytosis · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NQ34-F1 | alphafold | PREDICTED | 72.37 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQ34.
Amino-acid sequence (198 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMEM9B?
The strongest Open Targets associations for TMEM9B are BMI-adjusted waist-hip ratio, waist-hip ratio, hemoglobin measurement, monocyte count and neutrophil count.
How long is the TMEM9B protein?
The Homo sapiens TMEM9B protein (UniProt Q9NQ34) is 198 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NQ34 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NQ34 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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