Nuclear receptor-interacting protein 3 (NRIP3)
Homo sapiens — UniProt Q9NQ35
Data last refreshed: (UniProt release unknown)
Key facts
Nuclear receptor-interacting protein 3 (NRIP3) is a protein from Homo sapiens identified by UniProt accession Q9NQ35, 241 residues long. MolForge cross-references it against 0 known binders and 54 disease associations.
- UniProt accession: Q9NQ35; gene symbol NRIP3.
- Organism: Homo sapiens.
- Length: 241 amino acids.
- Target class: Nuclear receptor.
- Top disease associations (Open Targets): BMI-adjusted waist-hip ratio, waist-hip ratio and platelet crit.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Nuclear receptor-interacting protein 3 |
|---|---|
| UniProt accession | Q9NQ35 |
| Gene | NRIP3 |
| Organism | Homo sapiens |
| Length | 241 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Nuclear receptor (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (54)
Diseases linked to this target (Open Targets).
- BMI-adjusted waist-hip ratio · score 0.23
- waist-hip ratio · score 0.16
- platelet crit · score 0.15
- neuroimaging measurement · score 0.13
- brain volume measurement · score 0.12
- lymphocyte count · score 0.12
- cortical surface area measurement · score 0.11
- Red cell distribution width · score 0.08
- basophil count · score 0.08
- hemoglobin measurement · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NQ35-F1 | alphafold | PREDICTED | 73.01 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQ35.
Amino-acid sequence (241 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NRIP3?
The strongest Open Targets associations for NRIP3 are BMI-adjusted waist-hip ratio, waist-hip ratio, platelet crit, neuroimaging measurement and brain volume measurement.
How long is the NRIP3 protein?
The Homo sapiens NRIP3 protein (UniProt Q9NQ35) is 241 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NQ35 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NQ35 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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