Signal peptide, CUB and EGF-like domain-containing protein 2 (SCUBE2)
Homo sapiens — UniProt Q9NQ36
Data last refreshed: (UniProt release unknown)
Key facts
Signal peptide, CUB and EGF-like domain-containing protein 2 (SCUBE2) is a protein from Homo sapiens identified by UniProt accession Q9NQ36, 999 residues long. MolForge cross-references it against 0 known binders and 155 disease associations.
- UniProt accession: Q9NQ36; gene symbol SCUBE2.
- Organism: Homo sapiens.
- Length: 999 amino acids.
- Top disease associations (Open Targets): total blood protein measurement, insomnia and Cerebral arteriovenous malformation.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Signal peptide, CUB and EGF-like domain-containing protein 2 |
|---|---|
| UniProt accession | Q9NQ36 |
| Gene | SCUBE2 |
| Organism | Homo sapiens |
| Length | 999 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (155)
Diseases linked to this target (Open Targets).
- total blood protein measurement · score 0.32
- insomnia · score 0.32
- Cerebral arteriovenous malformation · score 0.27
- forced expiratory volume · score 0.25
- waist-hip ratio · score 0.24
- mean corpuscular volume · score 0.20
- breast cancer · score 0.08
- BMI-adjusted waist-hip ratio · score 0.07
- Red cell distribution width · score 0.06
- FEV/FVC ratio · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NQ36-F1 | alphafold | PREDICTED | 72.56 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQ36.
Amino-acid sequence (999 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SCUBE2?
The strongest Open Targets associations for SCUBE2 are total blood protein measurement, insomnia, Cerebral arteriovenous malformation, forced expiratory volume and waist-hip ratio.
How long is the SCUBE2 protein?
The Homo sapiens SCUBE2 protein (UniProt Q9NQ36) is 999 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NQ36 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NQ36 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.