Solute carrier family 52, riboflavin transporter, member 3 (SLC52A3)
Homo sapiens — UniProt Q9NQ40
Data last refreshed: (UniProt release unknown)
Key facts
Solute carrier family 52, riboflavin transporter, member 3 (SLC52A3) is a protein from Homo sapiens identified by UniProt accession Q9NQ40, 469 residues long. MolForge cross-references it against 0 known binders and 75 disease associations.
- UniProt accession: Q9NQ40; gene symbol SLC52A3.
- Organism: Homo sapiens.
- Length: 469 amino acids.
- Target class: Transporter.
- Top disease associations (Open Targets): Brown-Vialetto-van Laere syndrome 1, progressive bulbar palsy of childhood and genetic disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Solute carrier family 52, riboflavin transporter, member 3 |
|---|---|
| UniProt accession | Q9NQ40 |
| Gene | SLC52A3 |
| Organism | Homo sapiens |
| Length | 469 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Transporter (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (75)
Diseases linked to this target (Open Targets).
- Brown-Vialetto-van Laere syndrome 1 · score 0.83
- progressive bulbar palsy of childhood · score 0.71
- genetic disorder · score 0.52
- riboflavin transporter deficiency · score 0.46
- distal hereditary motor neuropathy · score 0.46
- progressive bulbar palsy · score 0.37
- auditory neuropathy · score 0.33
- body height · score 0.28
- Madras motor neuron disease · score 0.27
- prostate carcinoma · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NQ40-F1 | alphafold | PREDICTED | 80.35 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQ40.
Amino-acid sequence (469 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC52A3?
The strongest Open Targets associations for SLC52A3 are Brown-Vialetto-van Laere syndrome 1, progressive bulbar palsy of childhood, genetic disorder, riboflavin transporter deficiency and distal hereditary motor neuropathy.
How long is the SLC52A3 protein?
The Homo sapiens SLC52A3 protein (UniProt Q9NQ40) is 469 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NQ40 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NQ40 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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