Large ribosomal subunit protein mL40 (MRPL40)
Homo sapiens — UniProt Q9NQ50
Data last refreshed: (UniProt release unknown)
Key facts
Large ribosomal subunit protein mL40 (MRPL40) is a protein from Homo sapiens identified by UniProt accession Q9NQ50, 206 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.
- UniProt accession: Q9NQ50; gene symbol MRPL40.
- Organism: Homo sapiens.
- Length: 206 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, cryptorchidism and male infertility.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Large ribosomal subunit protein mL40 |
|---|---|
| UniProt accession | Q9NQ50 |
| Gene | MRPL40 |
| Organism | Homo sapiens |
| Length | 206 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (20)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.25
- cryptorchidism · score 0.04
- male infertility · score 0.01
- systemic juvenile idiopathic arthritis · score 0.01
- 22q11.2 deletion syndrome · score 0.01
- Alzheimer disease · score 0.01
- breast carcinoma · score 0.01
- Microcephaly · score 0.01
- neoplasm · score 0.00
- psychosis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NQ50-F1 | alphafold | PREDICTED | 78.75 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQ50.
Amino-acid sequence (206 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MRPL40?
The strongest Open Targets associations for MRPL40 are neurodegenerative disease, cryptorchidism, male infertility, systemic juvenile idiopathic arthritis and 22q11.2 deletion syndrome.
How long is the MRPL40 protein?
The Homo sapiens MRPL40 protein (UniProt Q9NQ50) is 206 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NQ50 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NQ50 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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