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Equatorin (EQTN)

Homo sapiens — UniProt Q9NQ60

Gene: EQTNHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Equatorin (EQTN) is a protein from Homo sapiens identified by UniProt accession Q9NQ60, 294 residues long. MolForge cross-references it against 0 known binders and 95 disease associations.

  • UniProt accession: Q9NQ60; gene symbol EQTN.
  • Organism: Homo sapiens.
  • Length: 294 amino acids.
  • Top disease associations (Open Targets): heel bone mineral density, blood protein measurement and angiopoietin-1 receptor, soluble measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameEquatorin
UniProt accessionQ9NQ60
GeneEQTN
OrganismHomo sapiens
Length294 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (95)

Diseases linked to this target (Open Targets).

  • heel bone mineral density · score 0.32
  • blood protein measurement · score 0.14
  • angiopoietin-1 receptor, soluble measurement · score 0.10
  • angiopoietin-2 receptor measurement · score 0.10
  • endothelial growth factor measurement · score 0.10
  • azoospermia · score 0.08
  • male infertility with teratozoospermia due to single gene mutation · score 0.08
  • partial chromosome Y deletion · score 0.07
  • Rare genetic female infertility · score 0.06
  • congenital bilateral absence of vas deferens · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9NQ60-F1alphafoldPREDICTED58.89—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQ60.

Amino-acid sequence (294 residues)

MNFILFIFIP GVFSLKSSTL KPTIEALPNV LPLNEDVNKQ EEKNEDHTPN YAPANEKNGN YYKDIKQYVF TTQNPNGTES EISVRATTDL NFALKNDKTV NATTYEKSTI EEETTTSEPS HKNIQRSTPN VPAFWTMLAK AINGTAVVMD DKDQLFHPIP ESDVNATQGE NQPDLEDLKI KIMLGISLMT LLLFVVLLAF CSATLYKLRH LSYKSCESQY SVNPELATMS YFHPSEGVSD TSFSKSAESS TFLGTTSSDM RRSGTRTSES KIMTDIISIG SDNEMHENDE SVTR

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with EQTN?

The strongest Open Targets associations for EQTN are heel bone mineral density, blood protein measurement, angiopoietin-1 receptor, soluble measurement, angiopoietin-2 receptor measurement and endothelial growth factor measurement.

How long is the EQTN protein?

The Homo sapiens EQTN protein (UniProt Q9NQ60) is 294 amino acids long.

Browse: Targets: E · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9NQ60
GeneEQTN
OrganismHomo sapiens
Length294
Binders0
Diseases95
View on UniProt