LIM/homeobox protein Lhx9 (LHX9)
Homo sapiens — UniProt Q9NQ69
Data last refreshed: (UniProt release unknown)
Key facts
LIM/homeobox protein Lhx9 (LHX9) is a protein from Homo sapiens identified by UniProt accession Q9NQ69, 397 residues long. MolForge cross-references it against 0 known binders and 237 disease associations.
- UniProt accession: Q9NQ69; gene symbol LHX9.
- Organism: Homo sapiens.
- Length: 397 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, sex hormone-binding globulin measurement and self reported educational attainment.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | LIM/homeobox protein Lhx9 |
|---|---|
| UniProt accession | Q9NQ69 |
| Gene | LHX9 |
| Organism | Homo sapiens |
| Length | 397 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (237)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.52
- sex hormone-binding globulin measurement · score 0.37
- self reported educational attainment · score 0.35
- heel bone mineral density · score 0.34
- risk-taking behaviour · score 0.30
- sleep measurement · score 0.28
- creatinine clearance measurement · score 0.26
- eosinophil count · score 0.24
- breast milk measurement · score 0.14
- pituitary stalk interruption syndrome · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NQ69-F1 | alphafold | PREDICTED | 65.86 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQ69.
Amino-acid sequence (397 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LHX9?
The strongest Open Targets associations for LHX9 are neurodegenerative disease, sex hormone-binding globulin measurement, self reported educational attainment, heel bone mineral density and risk-taking behaviour.
How long is the LHX9 protein?
The Homo sapiens LHX9 protein (UniProt Q9NQ69) is 397 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NQ69 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NQ69 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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