Cas scaffolding protein family member 4 (CASS4)
Homo sapiens — UniProt Q9NQ75
Data last refreshed: (UniProt release unknown)
Key facts
Cas scaffolding protein family member 4 (CASS4) is a protein from Homo sapiens identified by UniProt accession Q9NQ75, 786 residues long. MolForge cross-references it against 0 known binders and 46 disease associations.
- UniProt accession: Q9NQ75; gene symbol CASS4.
- Organism: Homo sapiens.
- Length: 786 amino acids.
- Top disease associations (Open Targets): Alzheimer disease, family history of Alzheimer’s disease and platelet count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cas scaffolding protein family member 4 |
|---|---|
| UniProt accession | Q9NQ75 |
| Gene | CASS4 |
| Organism | Homo sapiens |
| Length | 786 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (46)
Diseases linked to this target (Open Targets).
- Alzheimer disease · score 0.38
- family history of Alzheimer’s disease · score 0.38
- platelet count · score 0.37
- platelet crit · score 0.33
- protein measurement · score 0.29
- late-onset Alzheimers disease · score 0.29
- genetic disorder · score 0.12
- reticulocyte count · score 0.04
- non-small cell lung carcinoma · score 0.04
- body height · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NQ75-F1 | alphafold | PREDICTED | 58.54 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQ75.
Amino-acid sequence (786 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CASS4?
The strongest Open Targets associations for CASS4 are Alzheimer disease, family history of Alzheimer’s disease, platelet count, platelet crit and protein measurement.
How long is the CASS4 protein?
The Homo sapiens CASS4 protein (UniProt Q9NQ75) is 786 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NQ75 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NQ75 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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