Cartilage acidic protein 1 (CRTAC1)
Homo sapiens — UniProt Q9NQ79
Data last refreshed: (UniProt release unknown)
Key facts
Cartilage acidic protein 1 (CRTAC1) is a protein from Homo sapiens identified by UniProt accession Q9NQ79, 661 residues long. MolForge cross-references it against 0 known binders and 89 disease associations.
- UniProt accession: Q9NQ79; gene symbol CRTAC1.
- Organism: Homo sapiens.
- Length: 661 amino acids.
- Top disease associations (Open Targets): body fat percentage, body mass index and lean body mass.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cartilage acidic protein 1 |
|---|---|
| UniProt accession | Q9NQ79 |
| Gene | CRTAC1 |
| Organism | Homo sapiens |
| Length | 661 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (89)
Diseases linked to this target (Open Targets).
- body fat percentage · score 0.50
- body mass index · score 0.49
- lean body mass · score 0.49
- high density lipoprotein cholesterol measurement · score 0.48
- triglyceride measurement · score 0.45
- fat body mass · score 0.44
- body weight · score 0.44
- C-reactive protein measurement · score 0.41
- grip strength measurement · score 0.41
- self reported educational attainment · score 0.39
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NQ79-F1 | alphafold | PREDICTED | 85.66 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQ79.
Amino-acid sequence (661 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CRTAC1?
The strongest Open Targets associations for CRTAC1 are body fat percentage, body mass index, lean body mass, high density lipoprotein cholesterol measurement and triglyceride measurement.
How long is the CRTAC1 protein?
The Homo sapiens CRTAC1 protein (UniProt Q9NQ79) is 661 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NQ79 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NQ79 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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