Anoctamin-2 (ANO2)
Homo sapiens — UniProt Q9NQ90
Data last refreshed: (UniProt release unknown)
Key facts
Anoctamin-2 (ANO2) is a protein from Homo sapiens identified by UniProt accession Q9NQ90, 998 residues long. MolForge cross-references it against 0 known binders and 56 disease associations.
- UniProt accession: Q9NQ90; gene symbol ANO2.
- Organism: Homo sapiens.
- Length: 998 amino acids.
- Top disease associations (Open Targets): protein measurement, brain measurement and cortical thickness.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Anoctamin-2 |
|---|---|
| UniProt accession | Q9NQ90 |
| Gene | ANO2 |
| Organism | Homo sapiens |
| Length | 998 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (56)
Diseases linked to this target (Open Targets).
- protein measurement · score 0.47
- brain measurement · score 0.38
- cortical thickness · score 0.38
- COVID-19 · score 0.37
- cortical surface area measurement · score 0.34
- blood coagulation disease · score 0.34
- adolescent idiopathic scoliosis · score 0.27
- panic disorder · score 0.26
- PHF-tau measurement · score 0.26
- neuroimaging measurement · score 0.26
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NQ90-F1 | alphafold | PREDICTED | 73.63 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQ90.
Amino-acid sequence (998 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ANO2?
The strongest Open Targets associations for ANO2 are protein measurement, brain measurement, cortical thickness, COVID-19 and cortical surface area measurement.
How long is the ANO2 protein?
The Homo sapiens ANO2 protein (UniProt Q9NQ90) is 998 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NQ90 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NQ90 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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