Coordinator of PRMT5 and differentiation stimulator (COPRS)
Homo sapiens — UniProt Q9NQ92
Data last refreshed: (UniProt release unknown)
Key facts
Coordinator of PRMT5 and differentiation stimulator (COPRS) is a protein from Homo sapiens identified by UniProt accession Q9NQ92, 184 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.
- UniProt accession: Q9NQ92; gene symbol COPRS.
- Organism: Homo sapiens.
- Length: 184 amino acids.
- Top disease associations (Open Targets): prostate carcinoma, PHF-tau measurement and pulse pressure measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Coordinator of PRMT5 and differentiation stimulator |
|---|---|
| UniProt accession | Q9NQ92 |
| Gene | COPRS |
| Organism | Homo sapiens |
| Length | 184 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (25)
Diseases linked to this target (Open Targets).
- prostate carcinoma · score 0.33
- PHF-tau measurement · score 0.27
- pulse pressure measurement · score 0.26
- eosinophil count · score 0.26
- systolic blood pressure · score 0.22
- aortic measurement · score 0.22
- coronary artery disease · score 0.21
- forced expiratory volume · score 0.18
- gastric adenocarcinoma · score 0.11
- vital capacity · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NQ92-F1 | alphafold | PREDICTED | 62.00 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQ92.
Amino-acid sequence (184 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with COPRS?
The strongest Open Targets associations for COPRS are prostate carcinoma, PHF-tau measurement, pulse pressure measurement, eosinophil count and systolic blood pressure.
How long is the COPRS protein?
The Homo sapiens COPRS protein (UniProt Q9NQ92) is 184 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NQ92 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NQ92 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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