Thymus-specific serine protease (PRSS16)
Homo sapiens — UniProt Q9NQE7
Data last refreshed: (UniProt release unknown)
Key facts
Thymus-specific serine protease (PRSS16) is a protein from Homo sapiens identified by UniProt accession Q9NQE7, 514 residues long. MolForge cross-references it against 0 known binders and 91 disease associations.
- UniProt accession: Q9NQE7; gene symbol PRSS16.
- Organism: Homo sapiens.
- Length: 514 amino acids.
- Top disease associations (Open Targets): BMI-adjusted waist-hip ratio, gout and hemoglobin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Thymus-specific serine protease |
|---|---|
| UniProt accession | Q9NQE7 |
| Gene | PRSS16 |
| Organism | Homo sapiens |
| Length | 514 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (91)
Diseases linked to this target (Open Targets).
- BMI-adjusted waist-hip ratio · score 0.33
- gout · score 0.25
- hemoglobin measurement · score 0.24
- diet measurement · score 0.21
- wellbeing measurement · score 0.20
- schizophrenia · score 0.20
- transferrin saturation measurement · score 0.18
- total iron binding capacity · score 0.18
- BMI-adjusted hip circumference · score 0.18
- thyroid disease · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NQE7-F1 | alphafold | PREDICTED | 89.53 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQE7.
Amino-acid sequence (514 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PRSS16?
The strongest Open Targets associations for PRSS16 are BMI-adjusted waist-hip ratio, gout, hemoglobin measurement, diet measurement and wellbeing measurement.
How long is the PRSS16 protein?
The Homo sapiens PRSS16 protein (UniProt Q9NQE7) is 514 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NQE7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NQE7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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