Adenosine 5'-monophosphoramidase HINT3 (HINT3)
Homo sapiens — UniProt Q9NQE9
Data last refreshed: (UniProt release unknown)
Key facts
Adenosine 5'-monophosphoramidase HINT3 (HINT3) is a protein from Homo sapiens identified by UniProt accession Q9NQE9, 182 residues long. MolForge cross-references it against 0 known binders and 36 disease associations.
- UniProt accession: Q9NQE9; gene symbol HINT3.
- Organism: Homo sapiens.
- Length: 182 amino acids.
- Top disease associations (Open Targets): IGF-1 measurement, heel bone mineral density and urate measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Adenosine 5'-monophosphoramidase HINT3 |
|---|---|
| UniProt accession | Q9NQE9 |
| Gene | HINT3 |
| Organism | Homo sapiens |
| Length | 182 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (36)
Diseases linked to this target (Open Targets).
- IGF-1 measurement · score 0.17
- heel bone mineral density · score 0.14
- urate measurement · score 0.09
- creatinine measurement · score 0.09
- hemoglobin measurement · score 0.09
- erythrocyte count · score 0.09
- hematocrit · score 0.08
- Immature Reticulocyte Fraction Measurement · score 0.08
- BMI-adjusted hip circumference · score 0.08
- systolic blood pressure · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NQE9-F1 | alphafold | PREDICTED | 85.01 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQE9.
Amino-acid sequence (182 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with HINT3?
The strongest Open Targets associations for HINT3 are IGF-1 measurement, heel bone mineral density, urate measurement, creatinine measurement and hemoglobin measurement.
How long is the HINT3 protein?
The Homo sapiens HINT3 protein (UniProt Q9NQE9) is 182 amino acids long.
Browse: Targets: H · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NQE9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NQE9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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