Regulation of nuclear pre-mRNA domain-containing protein 1B (RPRD1B)
Homo sapiens — UniProt Q9NQG5
Data last refreshed: (UniProt release unknown)
Key facts
Regulation of nuclear pre-mRNA domain-containing protein 1B (RPRD1B) is a protein from Homo sapiens identified by UniProt accession Q9NQG5, 326 residues long. MolForge cross-references it against 0 known binders and 113 disease associations.
- UniProt accession: Q9NQG5; gene symbol RPRD1B.
- Organism: Homo sapiens.
- Length: 326 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, gastric carcinoma and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Regulation of nuclear pre-mRNA domain-containing protein 1B |
|---|---|
| UniProt accession | Q9NQG5 |
| Gene | RPRD1B |
| Organism | Homo sapiens |
| Length | 326 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (113)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.40
- gastric carcinoma · score 0.15
- neoplasm · score 0.11
- non-small cell lung carcinoma · score 0.08
- oral squamous cell carcinoma · score 0.08
- melanoma · score 0.07
- renal cell carcinoma · score 0.07
- pancreatic neoplasm · score 0.07
- gonorrhea · score 0.06
- hereditary persistence of fetal hemoglobin-sickle cell disease syndrome · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NQG5-F1 | alphafold | PREDICTED | 82.74 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQG5.
Amino-acid sequence (326 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RPRD1B?
The strongest Open Targets associations for RPRD1B are neurodegenerative disease, gastric carcinoma, neoplasm, non-small cell lung carcinoma and oral squamous cell carcinoma.
How long is the RPRD1B protein?
The Homo sapiens RPRD1B protein (UniProt Q9NQG5) is 326 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NQG5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NQG5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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