Mitochondrial dynamics protein MIEF1 (MIEF1)
Homo sapiens — UniProt Q9NQG6
Data last refreshed: (UniProt release unknown)
Key facts
Mitochondrial dynamics protein MIEF1 (MIEF1) is a protein from Homo sapiens identified by UniProt accession Q9NQG6, 463 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.
- UniProt accession: Q9NQG6; gene symbol MIEF1.
- Organism: Homo sapiens.
- Length: 463 amino acids.
- Top disease associations (Open Targets): alkaline phosphatase measurement, reticulocyte measurement and mean corpuscular volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Mitochondrial dynamics protein MIEF1 |
|---|---|
| UniProt accession | Q9NQG6 |
| Gene | MIEF1 |
| Organism | Homo sapiens |
| Length | 463 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (38)
Diseases linked to this target (Open Targets).
- alkaline phosphatase measurement · score 0.31
- reticulocyte measurement · score 0.17
- mean corpuscular volume · score 0.12
- mean corpuscular hemoglobin concentration · score 0.10
- mean corpuscular hemoglobin · score 0.10
- red blood cell density measurement · score 0.09
- Immature Reticulocyte Fraction Measurement · score 0.08
- protein measurement · score 0.07
- platelet crit · score 0.06
- triple-negative breast cancer · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NQG6-F1 | alphafold | PREDICTED | 78.10 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQG6.
Amino-acid sequence (463 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MIEF1?
The strongest Open Targets associations for MIEF1 are alkaline phosphatase measurement, reticulocyte measurement, mean corpuscular volume, mean corpuscular hemoglobin concentration and mean corpuscular hemoglobin.
How long is the MIEF1 protein?
The Homo sapiens MIEF1 protein (UniProt Q9NQG6) is 463 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NQG6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NQG6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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