Xaa-Pro aminopeptidase 3 (XPNPEP3)
Homo sapiens — UniProt Q9NQH7
Data last refreshed: (UniProt release unknown)
Key facts
Xaa-Pro aminopeptidase 3 (XPNPEP3) is a protein from Homo sapiens identified by UniProt accession Q9NQH7, 507 residues long. MolForge cross-references it against 0 known binders and 52 disease associations.
- UniProt accession: Q9NQH7; gene symbol XPNPEP3.
- Organism: Homo sapiens.
- Length: 507 amino acids.
- Top disease associations (Open Targets): nephronophthisis, late-onset nephronophthisis and low density lipoprotein cholesterol measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Xaa-Pro aminopeptidase 3 |
|---|---|
| UniProt accession | Q9NQH7 |
| Gene | XPNPEP3 |
| Organism | Homo sapiens |
| Length | 507 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (52)
Diseases linked to this target (Open Targets).
- nephronophthisis · score 0.76
- late-onset nephronophthisis · score 0.37
- low density lipoprotein cholesterol measurement · score 0.30
- total cholesterol measurement · score 0.28
- apolipoprotein B measurement · score 0.27
- C-reactive protein measurement · score 0.22
- bipolar disorder · score 0.20
- genetic disorder · score 0.19
- kidney disease · score 0.17
- vitamin D measurement · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NQH7-F1 | alphafold | PREDICTED | 91.91 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQH7.
Amino-acid sequence (507 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with XPNPEP3?
The strongest Open Targets associations for XPNPEP3 are nephronophthisis, late-onset nephronophthisis, low density lipoprotein cholesterol measurement, total cholesterol measurement and apolipoprotein B measurement.
How long is the XPNPEP3 protein?
The Homo sapiens XPNPEP3 protein (UniProt Q9NQH7) is 507 amino acids long.
Browse: Targets: X · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NQH7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NQH7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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