Omega-amidase NIT2 (NIT2)
Homo sapiens — UniProt Q9NQR4
Data last refreshed: (UniProt release unknown)
Key facts
Omega-amidase NIT2 (NIT2) is a protein from Homo sapiens identified by UniProt accession Q9NQR4, 276 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.
- UniProt accession: Q9NQR4; gene symbol NIT2.
- Organism: Homo sapiens.
- Length: 276 amino acids.
- Top disease associations (Open Targets): refractive error, lung adenocarcinoma and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Omega-amidase NIT2 |
|---|---|
| UniProt accession | Q9NQR4 |
| Gene | NIT2 |
| Organism | Homo sapiens |
| Length | 276 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (18)
Diseases linked to this target (Open Targets).
- refractive error · score 0.10
- lung adenocarcinoma · score 0.07
- neoplasm · score 0.07
- colorectal cancer · score 0.01
- ulcerative colitis · score 0.01
- Alzheimer disease · score 0.01
- cancer · score 0.01
- systemic juvenile idiopathic arthritis · score 0.01
- infect · score 0.01
- infection · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NQR4-F1 | alphafold | PREDICTED | 97.64 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQR4.
Amino-acid sequence (276 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NIT2?
The strongest Open Targets associations for NIT2 are refractive error, lung adenocarcinoma, neoplasm, colorectal cancer and ulcerative colitis.
How long is the NIT2 protein?
The Homo sapiens NIT2 protein (UniProt Q9NQR4) is 276 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NQR4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NQR4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.