Coiled-coil domain-containing protein 177 (CCDC177)
Homo sapiens — UniProt Q9NQR7
Data last refreshed: (UniProt release unknown)
Key facts
Coiled-coil domain-containing protein 177 (CCDC177) is a protein from Homo sapiens identified by UniProt accession Q9NQR7, 707 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.
- UniProt accession: Q9NQR7; gene symbol CCDC177.
- Organism: Homo sapiens.
- Length: 707 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, astrocytoma and glioblastoma multiforme.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Coiled-coil domain-containing protein 177 |
|---|---|
| UniProt accession | Q9NQR7 |
| Gene | CCDC177 |
| Organism | Homo sapiens |
| Length | 707 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (11)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.29
- astrocytoma · score 0.02
- glioblastoma multiforme · score 0.02
- hair shape measurement · score 0.02
- neoplasm · score 0.02
- Ataxia-telangiectasia · score 0.02
- coronary artery disease · score 0.01
- small cell lung carcinoma · score 0.01
- head and neck squamous cell carcinoma · score 0.00
- idiopathic hemiconvulsion-hemiplegia syndrome · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NQR7-F1 | alphafold | PREDICTED | 73.06 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQR7.
Amino-acid sequence (707 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CCDC177?
The strongest Open Targets associations for CCDC177 are neurodegenerative disease, astrocytoma, glioblastoma multiforme, hair shape measurement and neoplasm.
How long is the CCDC177 protein?
The Homo sapiens CCDC177 protein (UniProt Q9NQR7) is 707 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NQR7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NQR7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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