Cell death regulator Aven (AVEN)
Homo sapiens — UniProt Q9NQS1
Data last refreshed: (UniProt release unknown)
Key facts
Cell death regulator Aven (AVEN) is a protein from Homo sapiens identified by UniProt accession Q9NQS1, 362 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.
- UniProt accession: Q9NQS1; gene symbol AVEN.
- Organism: Homo sapiens.
- Length: 362 amino acids.
- Top disease associations (Open Targets): protein measurement, gonorrhea and myocardial infarction.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cell death regulator Aven |
|---|---|
| UniProt accession | Q9NQS1 |
| Gene | AVEN |
| Organism | Homo sapiens |
| Length | 362 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (29)
Diseases linked to this target (Open Targets).
- protein measurement · score 0.03
- gonorrhea · score 0.02
- myocardial infarction · score 0.02
- acute myeloid leukemia · score 0.02
- lung adenocarcinoma · score 0.01
- cancer · score 0.01
- ovarian carcinoma · score 0.01
- neoplasm · score 0.01
- Acute Leukemia · score 0.01
- Tetralogy of Fallot · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NQS1-F1 | alphafold | PREDICTED | 57.55 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQS1.
Amino-acid sequence (362 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with AVEN?
The strongest Open Targets associations for AVEN are protein measurement, gonorrhea, myocardial infarction, acute myeloid leukemia and lung adenocarcinoma.
How long is the AVEN protein?
The Homo sapiens AVEN protein (UniProt Q9NQS1) is 362 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NQS1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NQS1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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