Nectin-3 (NECTIN3)
Homo sapiens — UniProt Q9NQS3
Data last refreshed: (UniProt release unknown)
Key facts
Nectin-3 (NECTIN3) is a protein from Homo sapiens identified by UniProt accession Q9NQS3, 549 residues long. MolForge cross-references it against 0 known binders and 224 disease associations.
- UniProt accession: Q9NQS3; gene symbol NECTIN3.
- Organism: Homo sapiens.
- Length: 549 amino acids.
- Top disease associations (Open Targets): early-onset non-syndromic cataract, Developmental cataract and mathematical ability.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Nectin-3 |
|---|---|
| UniProt accession | Q9NQS3 |
| Gene | NECTIN3 |
| Organism | Homo sapiens |
| Length | 549 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (224)
Diseases linked to this target (Open Targets).
- early-onset non-syndromic cataract · score 0.27
- Developmental cataract · score 0.26
- mathematical ability · score 0.25
- hair shape measurement · score 0.19
- balding measurement · score 0.19
- Hypomaturation amelogenesis imperfecta · score 0.09
- Hypoplastic amelogenesis imperfecta · score 0.09
- tooth agenesis · score 0.08
- Familial ocular anterior segment mesenchymal dysgenesis · score 0.07
- congenital primary aphakia · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NQS3-F1 | alphafold | PREDICTED | 73.42 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQS3.
Amino-acid sequence (549 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NECTIN3?
The strongest Open Targets associations for NECTIN3 are early-onset non-syndromic cataract, Developmental cataract, mathematical ability, hair shape measurement and balding measurement.
How long is the NECTIN3 protein?
The Homo sapiens NECTIN3 protein (UniProt Q9NQS3) is 549 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NQS3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NQS3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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