Inner centromere protein (INCENP)
Homo sapiens — UniProt Q9NQS7
Data last refreshed: (UniProt release unknown)
Key facts
Inner centromere protein (INCENP) is a protein from Homo sapiens identified by UniProt accession Q9NQS7, 918 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.
- UniProt accession: Q9NQS7; gene symbol INCENP.
- Organism: Homo sapiens.
- Length: 918 amino acids.
- Top disease associations (Open Targets): prostate carcinoma, sex hormone-binding globulin measurement and nephronophthisis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Inner centromere protein |
|---|---|
| UniProt accession | Q9NQS7 |
| Gene | INCENP |
| Organism | Homo sapiens |
| Length | 918 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (44)
Diseases linked to this target (Open Targets).
- prostate carcinoma · score 0.28
- sex hormone-binding globulin measurement · score 0.28
- nephronophthisis · score 0.26
- endometrial cancer · score 0.23
- breast adenocarcinoma · score 0.23
- glioblastoma multiforme · score 0.20
- esophageal cancer · score 0.14
- phosphatidylcholine measurement · score 0.13
- Red cell distribution width · score 0.11
- ovarian carcinoma · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NQS7-F1 | alphafold | PREDICTED | 59.30 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQS7.
Amino-acid sequence (918 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with INCENP?
The strongest Open Targets associations for INCENP are prostate carcinoma, sex hormone-binding globulin measurement, nephronophthisis, endometrial cancer and breast adenocarcinoma.
How long is the INCENP protein?
The Homo sapiens INCENP protein (UniProt Q9NQS7) is 918 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NQS7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NQS7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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