Fascin-3 (FSCN3)
Homo sapiens — UniProt Q9NQT6
Data last refreshed: (UniProt release unknown)
Key facts
Fascin-3 (FSCN3) is a protein from Homo sapiens identified by UniProt accession Q9NQT6, 498 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.
- UniProt accession: Q9NQT6; gene symbol FSCN3.
- Organism: Homo sapiens.
- Length: 498 amino acids.
- Top disease associations (Open Targets): type 2 diabetes mellitus, intelligence and cognitive function measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Fascin-3 |
|---|---|
| UniProt accession | Q9NQT6 |
| Gene | FSCN3 |
| Organism | Homo sapiens |
| Length | 498 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (23)
Diseases linked to this target (Open Targets).
- type 2 diabetes mellitus · score 0.24
- intelligence · score 0.22
- cognitive function measurement · score 0.22
- hypospadias · score 0.12
- genetic disorder · score 0.12
- Abnormality of refraction · score 0.09
- self reported educational attainment · score 0.08
- Cleft palate · score 0.04
- triglyceride measurement · score 0.03
- low density lipoprotein cholesterol measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NQT6-F1 | alphafold | PREDICTED | 92.17 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQT6.
Amino-acid sequence (498 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FSCN3?
The strongest Open Targets associations for FSCN3 are type 2 diabetes mellitus, intelligence, cognitive function measurement, hypospadias and genetic disorder.
How long is the FSCN3 protein?
The Homo sapiens FSCN3 protein (UniProt Q9NQT6) is 498 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NQT6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NQT6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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