PR domain-containing protein 11 (PRDM11)
Homo sapiens — UniProt Q9NQV5
Data last refreshed: (UniProt release unknown)
Key facts
PR domain-containing protein 11 (PRDM11) is a protein from Homo sapiens identified by UniProt accession Q9NQV5, 511 residues long. MolForge cross-references it against 0 known binders and 72 disease associations.
- UniProt accession: Q9NQV5; gene symbol PRDM11.
- Organism: Homo sapiens.
- Length: 511 amino acids.
- Top disease associations (Open Targets): neuroticism measurement, vital capacity and pulse pressure measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | PR domain-containing protein 11 |
|---|---|
| UniProt accession | Q9NQV5 |
| Gene | PRDM11 |
| Organism | Homo sapiens |
| Length | 511 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (72)
Diseases linked to this target (Open Targets).
- neuroticism measurement · score 0.49
- vital capacity · score 0.45
- pulse pressure measurement · score 0.43
- body height · score 0.42
- BMI-adjusted waist-hip ratio · score 0.41
- reaction time measurement · score 0.39
- systolic blood pressure · score 0.38
- Thyrotoxicosis · score 0.36
- forced expiratory volume · score 0.34
- hemoglobin A1 measurement · score 0.34
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NQV5-F1 | alphafold | PREDICTED | 61.24 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQV5.
Amino-acid sequence (511 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PRDM11?
The strongest Open Targets associations for PRDM11 are neuroticism measurement, vital capacity, pulse pressure measurement, body height and BMI-adjusted waist-hip ratio.
How long is the PRDM11 protein?
The Homo sapiens PRDM11 protein (UniProt Q9NQV5) is 511 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NQV5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NQV5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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