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PR domain zinc finger protein 10 (PRDM10)

Homo sapiens — UniProt Q9NQV6

Gene: PRDM10Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

PR domain zinc finger protein 10 (PRDM10) is a protein from Homo sapiens identified by UniProt accession Q9NQV6, 1147 residues long. MolForge cross-references it against 0 known binders and 80 disease associations.

  • UniProt accession: Q9NQV6; gene symbol PRDM10.
  • Organism: Homo sapiens.
  • Length: 1147 amino acids.
  • Top disease associations (Open Targets): Birt-Hogg-Dubé syndrome, PHF-tau measurement and neurodegenerative disease.
  • 3D structure: AlphaFold model available.

Target properties

Protein namePR domain zinc finger protein 10
UniProt accessionQ9NQV6
GenePRDM10
OrganismHomo sapiens
Length1147 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (80)

Diseases linked to this target (Open Targets).

  • Birt-Hogg-Dubé syndrome · score 0.37
  • PHF-tau measurement · score 0.33
  • neurodegenerative disease · score 0.29
  • viral load · score 0.27
  • sign or symptom · score 0.23
  • protein measurement · score 0.23
  • Red cell distribution width · score 0.14
  • benign lipomatous neoplasm · score 0.11
  • lipoma · score 0.09
  • breast carcinoma · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9NQV6-F1alphafoldPREDICTED54.94—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQV6.

Amino-acid sequence (1147 residues)

MDSKDESSHV WPTSAEHEQN AAQVHFVPDT GTVAQIVYTD DQVRPPQQVV YTADGASYTS VDGPEHTLVY IHPVEAAQTL FTDPGQVAYV QQDATAQQAS LPVHNQVLPS IESVDGSDPL ATLQTPLGRL EAKEEEDEDE DEDTEEDEEE DGEDTDLDDW EPDPPRPFDP HDLWCEECNN AHASVCPKHG PLHPIPNRPV LTRARASLPL VLYIDRFLGG VFSKRRIPKR TQFGPVEGPL VRGSELKDCY IHLKVSLDKG DRKERDLHED LWFELSDETL CNWMMFVRPA QNHLEQNLVA YQYGHHVYYT TIKNVEPKQE LKVWYAASYA EFVNQKIHDI SEEERKVLRE QEKNWPCYEC NRRFISSEQL QQHLNSHDEK LDVFSRTRGR GRGRGKRRFG PGRRPGRPPK FIRLEITSEN GEKSDDGTQD LLHFPTKEQF DEAEPATLNG LDQPEQTTIP IPQLPQETQS SLEHEPETHT LHLQPQHEES VVPTQSTLTA DDMRRAKRIR LELQNAALQH LFIRKSFRPF KCLQCGKAFR EKDKLDQHLR FHGREGNCPL TCDLCNKGFI SSTSLESHMK LHSDQKTYSC IFCPESFDRL DLLKDHVAIH INDGYFTCPT CKKRFPDFIQ VKKHVRSFHS EKIYQCTECD KAFCRPDKLR LHMLRHSDRK DFLCSTCGKQ FKRKDKLREH MQRMHNPERE AKKADRISRS KTFKPRITST DYDSFTFKCR LCMMGFRRRG MLVNHLSKRH PDMKIEEVPE LTLPIIKPNR DYFCQYCDKV YKSASKRKAH ILKNHPGAEL PPSIRKLRPA GPGEPDPMLS THTQLTGTIA TPPVCCPHCS KQYSSKTKMV QHIRKKHPEF AQLSNTIHTP LTTAVISATP AVLTTDSATG ETVVTTDLLT QAMTELSQTL TTDYRTPQGD YQRIQYIPVS QSASGLQQPQ HIQLQVVQVA SATSPHQSQQ STVDVGQLHD PQPYPQHAIQ VQHIQVSGQP LSPSAQQAQQ GLSPSHIQGS SSTQGQALQQ QQQQQQNSSV QHTYLPSAWN SFRGYSSEIQ MMTLPPGQFV ITDSGVATPV TTGQVKAVTS GHYVLSESQS ELEEKQTSAL SGGVQVEPPA HSDSLDPQTN SQQQTTQYII TTTTNGNGSS EVHITKP

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with PRDM10?

The strongest Open Targets associations for PRDM10 are Birt-Hogg-Dubé syndrome, PHF-tau measurement, neurodegenerative disease, viral load and sign or symptom.

How long is the PRDM10 protein?

The Homo sapiens PRDM10 protein (UniProt Q9NQV6) is 1147 amino acids long.

Browse: Targets: P · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9NQV6
GenePRDM10
OrganismHomo sapiens
Length1147
Binders0
Diseases80
View on UniProt