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Protein transport protein Sec31B (SEC31B)

Homo sapiens — UniProt Q9NQW1

Gene: SEC31BHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Protein transport protein Sec31B (SEC31B) is a protein from Homo sapiens identified by UniProt accession Q9NQW1, 1179 residues long. MolForge cross-references it against 0 known binders and 52 disease associations.

  • UniProt accession: Q9NQW1; gene symbol SEC31B.
  • Organism: Homo sapiens.
  • Length: 1179 amino acids.
  • Top disease associations (Open Targets): neurodegenerative disease, body height and mean platelet volume.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameProtein transport protein Sec31B
UniProt accessionQ9NQW1
GeneSEC31B
OrganismHomo sapiens
Length1179 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (52)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.54
  • body height · score 0.25
  • mean platelet volume · score 0.24
  • alkaline phosphatase measurement · score 0.21
  • heel bone mineral density · score 0.21
  • palmitoleic acid measurement · score 0.20
  • body mass index · score 0.20
  • lean body mass · score 0.19
  • fatty acid measurement · score 0.17
  • body weight · score 0.14

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9NQW1-F1alphafoldPREDICTED69.53—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQW1.

Amino-acid sequence (1179 residues)

MKLKELERPA VQAWSPASQY PLYLATGTSA QQLDSSFSTN GTLEIFEVDF RDPSLDLKHR GVLSALSRFH KLVWGSFGSG LLESSGVIVG GGDNGMLILY NVTHILSSGK EPVIAQKQKH TGAVRALDLN PFQGNLLASG ASDSEIFIWD LNNLNVPMTL GSKSQQPPED IKALSWNRQA QHILSSAHPS GKAVVWDLRK NEPIIKVSDH SNRMHCSGLA WHPDIATQLV LCSEDDRLPV IQLWDLRFAS SPLKVLESHS RGILSVSWSQ ADAELLLTSA KDSQILCRNL GSSEVVYKLP TQSSWCFDVQ WCPRDPSVFS AASFNGWISL YSVMGRSWEV QHMRQADKIS SSFSKGQPLP PLQVPEQVAQ APLIPPLKKP PKWIRRPTGV SFAFGGKLVT FGLPSTPAHL VPQPCPRLVF ISQVTTESEF LMRSAELQEA LGSGNLLNYC QNKSQQALLQ SEKMLWQFLK VTLEQDSRMK FLKLLGYSKD ELQKKVATWL KSDVGLGESP QPKGNDLNSD RQQAFCSQAS KHTTKEASAS SAFFDELVPQ NMTPWEIPIT KDIDGLLSQA LLLGELGPAV ELCLKEERFA DAIILAQAGG TDLLKQTQER YLAKKKTKIS SLLACVVQKN WKDVVCTCSL KNWREALALL LTYSGTEKFP ELCDMLGTRM EQEGSRALTS EARLCYVCSG SVERLVECWA KCHQALSPMA LQDLMEKVMV LNRSLEQLRG PHGVSPGPAT TYRVTQYANL LAAQGSLATA MSFLPRDCAQ PPVQQLRDRL FHAQGSAVLG QQSPPFPFPR IVVGATLHSK ETSSYRLGSQ PSHQVPTPSP RPRVFTPQSS PAMPLAPSHP SPYQGPRTQN ISDYRAPGPQ AIQPLPLSPG VRPASSQPQL LGGQRVQVPN PVGFPGTWPL PGSPLPMACP GIMRPGSTSL PETPRLFPLL PLRPLGPGRM VSHTPAPPAS FPVPYLPGDP GAPCSSVLPT TGILTPHPGP QDSWKEAPAP RGNLQRNKLP ETFMPPAPIT APVMSLTPEL QGILPSQPPV SSVSHAPPGV PGELSLQLQH LPPEKMERKE LPPEHQSLKS SFEALLQRCS LSATDLKTKR KLEEAAQRLE YLYEKLCEGT LSPHVVAGLH EVARCVDAGS FEQGLAVHAQ VAGCSSFSEV SSFMPILKAV LIIAHKLLV

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with SEC31B?

The strongest Open Targets associations for SEC31B are neurodegenerative disease, body height, mean platelet volume, alkaline phosphatase measurement and heel bone mineral density.

How long is the SEC31B protein?

The Homo sapiens SEC31B protein (UniProt Q9NQW1) is 1179 amino acids long.

Browse: Targets: S · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9NQW1
GeneSEC31B
OrganismHomo sapiens
Length1179
Binders0
Diseases52
View on UniProt