Histone-lysine N-methyltransferase PRDM7 (PRDM7)
Homo sapiens — UniProt Q9NQW5
Data last refreshed: (UniProt release unknown)
Key facts
Histone-lysine N-methyltransferase PRDM7 (PRDM7) is a protein from Homo sapiens identified by UniProt accession Q9NQW5, 492 residues long. MolForge cross-references it against 0 known binders and 156 disease associations.
- UniProt accession: Q9NQW5; gene symbol PRDM7.
- Organism: Homo sapiens.
- Length: 492 amino acids.
- Top disease associations (Open Targets): sunburn, white matter microstructure measurement and suntan.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Histone-lysine N-methyltransferase PRDM7 |
|---|---|
| UniProt accession | Q9NQW5 |
| Gene | PRDM7 |
| Organism | Homo sapiens |
| Length | 492 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (156)
Diseases linked to this target (Open Targets).
- sunburn · score 0.36
- white matter microstructure measurement · score 0.30
- suntan · score 0.28
- mathematical ability · score 0.27
- mean corpuscular hemoglobin · score 0.26
- hair color · score 0.24
- cognitive function measurement · score 0.20
- azoospermia · score 0.10
- partial chromosome Y deletion · score 0.10
- spermatogenic failures 50 · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NQW5-F1 | alphafold | PREDICTED | 60.25 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQW5.
Amino-acid sequence (492 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PRDM7?
The strongest Open Targets associations for PRDM7 are sunburn, white matter microstructure measurement, suntan, mathematical ability and mean corpuscular hemoglobin.
How long is the PRDM7 protein?
The Homo sapiens PRDM7 protein (UniProt Q9NQW5) is 492 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NQW5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NQW5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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