Anillin (ANLN)
Homo sapiens — UniProt Q9NQW6
Data last refreshed: (UniProt release unknown)
Key facts
Anillin (ANLN) is a protein from Homo sapiens identified by UniProt accession Q9NQW6, 1124 residues long. MolForge cross-references it against 0 known binders and 181 disease associations.
- UniProt accession: Q9NQW6; gene symbol ANLN.
- Organism: Homo sapiens.
- Length: 1124 amino acids.
- Top disease associations (Open Targets): focal segmental glomerulosclerosis, familial idiopathic steroid-resistant nephrotic syndrome and Red cell distribution width.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Anillin |
|---|---|
| UniProt accession | Q9NQW6 |
| Gene | ANLN |
| Organism | Homo sapiens |
| Length | 1124 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (181)
Diseases linked to this target (Open Targets).
- focal segmental glomerulosclerosis · score 0.60
- familial idiopathic steroid-resistant nephrotic syndrome · score 0.58
- Red cell distribution width · score 0.46
- mean corpuscular volume · score 0.42
- mean reticulocyte volume · score 0.40
- mean corpuscular hemoglobin · score 0.38
- platelet count · score 0.35
- mean corpuscular hemoglobin concentration · score 0.28
- neurodegenerative disease · score 0.21
- reticulocyte count · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NQW6-F1 | alphafold | PREDICTED | 59.18 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQW6.
Amino-acid sequence (1124 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ANLN?
The strongest Open Targets associations for ANLN are focal segmental glomerulosclerosis, familial idiopathic steroid-resistant nephrotic syndrome, Red cell distribution width, mean corpuscular volume and mean reticulocyte volume.
How long is the ANLN protein?
The Homo sapiens ANLN protein (UniProt Q9NQW6) is 1124 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NQW6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NQW6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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