Xaa-Pro aminopeptidase 1 (XPNPEP1)
Homo sapiens — UniProt Q9NQW7
Data last refreshed: (UniProt release unknown)
Key facts
Xaa-Pro aminopeptidase 1 (XPNPEP1) is a protein from Homo sapiens identified by UniProt accession Q9NQW7, 623 residues long. MolForge cross-references it against 0 known binders and 100 disease associations.
- UniProt accession: Q9NQW7; gene symbol XPNPEP1.
- Organism: Homo sapiens.
- Length: 623 amino acids.
- Top disease associations (Open Targets): bipolar disorder, mean corpuscular hemoglobin concentration and eosinophil count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Xaa-Pro aminopeptidase 1 |
|---|---|
| UniProt accession | Q9NQW7 |
| Gene | XPNPEP1 |
| Organism | Homo sapiens |
| Length | 623 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (100)
Diseases linked to this target (Open Targets).
- bipolar disorder · score 0.37
- mean corpuscular hemoglobin concentration · score 0.36
- eosinophil count · score 0.31
- bipolar I disorder · score 0.29
- biliary atresia · score 0.28
- platelet count · score 0.26
- cortical surface area measurement · score 0.23
- monocyte count · score 0.21
- brain measurement · score 0.19
- mathematical ability · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NQW7-F1 | alphafold | PREDICTED | 96.98 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQW7.
Amino-acid sequence (623 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with XPNPEP1?
The strongest Open Targets associations for XPNPEP1 are bipolar disorder, mean corpuscular hemoglobin concentration, eosinophil count, bipolar I disorder and biliary atresia.
How long is the XPNPEP1 protein?
The Homo sapiens XPNPEP1 protein (UniProt Q9NQW7) is 623 amino acids long.
Browse: Targets: X · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NQW7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NQW7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.