Putative histone-lysine N-methyltransferase PRDM6 (PRDM6)
Homo sapiens — UniProt Q9NQX0
Data last refreshed: (UniProt release unknown)
Key facts
Putative histone-lysine N-methyltransferase PRDM6 (PRDM6) is a protein from Homo sapiens identified by UniProt accession Q9NQX0, 595 residues long. MolForge cross-references it against 0 known binders and 72 disease associations.
- UniProt accession: Q9NQX0; gene symbol PRDM6.
- Organism: Homo sapiens.
- Length: 595 amino acids.
- Top disease associations (Open Targets): persistent fetal circulation syndrome, electrocardiography and systolic blood pressure.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Putative histone-lysine N-methyltransferase PRDM6 |
|---|---|
| UniProt accession | Q9NQX0 |
| Gene | PRDM6 |
| Organism | Homo sapiens |
| Length | 595 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (72)
Diseases linked to this target (Open Targets).
- persistent fetal circulation syndrome · score 0.62
- electrocardiography · score 0.53
- systolic blood pressure · score 0.52
- neurodegenerative disease · score 0.50
- diastolic blood pressure · score 0.48
- hair shape measurement · score 0.46
- pulse pressure measurement · score 0.45
- hypertension · score 0.44
- aortic measurement · score 0.43
- Agents acting on the renin-angiotensin system use measurement · score 0.41
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NQX0-F1 | alphafold | PREDICTED | 56.17 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQX0.
Amino-acid sequence (595 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PRDM6?
The strongest Open Targets associations for PRDM6 are persistent fetal circulation syndrome, electrocardiography, systolic blood pressure, neurodegenerative disease and diastolic blood pressure.
How long is the PRDM6 protein?
The Homo sapiens PRDM6 protein (UniProt Q9NQX0) is 595 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NQX0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NQX0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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