PR domain zinc finger protein 5 (PRDM5)
Homo sapiens — UniProt Q9NQX1
Data last refreshed: (UniProt release unknown)
Key facts
PR domain zinc finger protein 5 (PRDM5) is a protein from Homo sapiens identified by UniProt accession Q9NQX1, 630 residues long. MolForge cross-references it against 0 known binders and 115 disease associations.
- UniProt accession: Q9NQX1; gene symbol PRDM5.
- Organism: Homo sapiens.
- Length: 630 amino acids.
- Top disease associations (Open Targets): brittle cornea syndrome, Abnormality of the cardiovascular system and Ehlers-Danlos syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | PR domain zinc finger protein 5 |
|---|---|
| UniProt accession | Q9NQX1 |
| Gene | PRDM5 |
| Organism | Homo sapiens |
| Length | 630 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (115)
Diseases linked to this target (Open Targets).
- brittle cornea syndrome · score 0.74
- Abnormality of the cardiovascular system · score 0.47
- Ehlers-Danlos syndrome · score 0.41
- Connective tissue disease with eye involvement · score 0.37
- cortical thickness · score 0.35
- cortical surface area measurement · score 0.35
- IGF-1 measurement · score 0.33
- type 2 diabetes mellitus · score 0.31
- insulin like growth factor measurement · score 0.29
- osteoarthritis · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NQX1-F1 | alphafold | PREDICTED | 72.24 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQX1.
Amino-acid sequence (630 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PRDM5?
The strongest Open Targets associations for PRDM5 are brittle cornea syndrome, Abnormality of the cardiovascular system, Ehlers-Danlos syndrome, Connective tissue disease with eye involvement and cortical thickness.
How long is the PRDM5 protein?
The Homo sapiens PRDM5 protein (UniProt Q9NQX1) is 630 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NQX1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NQX1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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