Neural proliferation differentiation and control protein 1 (NPDC1)
Homo sapiens — UniProt Q9NQX5
Data last refreshed: (UniProt release unknown)
Key facts
Neural proliferation differentiation and control protein 1 (NPDC1) is a protein from Homo sapiens identified by UniProt accession Q9NQX5, 325 residues long. MolForge cross-references it against 0 known binders and 27 disease associations.
- UniProt accession: Q9NQX5; gene symbol NPDC1.
- Organism: Homo sapiens.
- Length: 325 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, leukocyte count and neutrophil count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Neural proliferation differentiation and control protein 1 |
|---|---|
| UniProt accession | Q9NQX5 |
| Gene | NPDC1 |
| Organism | Homo sapiens |
| Length | 325 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (27)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.46
- leukocyte count · score 0.16
- neutrophil count · score 0.14
- myeloid white cell count · score 0.07
- monocyte percentage of leukocytes · score 0.05
- e-selectin measurement · score 0.04
- neoplasm · score 0.03
- lymphocyte count · score 0.02
- basophil count · score 0.02
- Dravet syndrome · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NQX5-F1 | alphafold | PREDICTED | 68.40 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQX5.
Amino-acid sequence (325 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NPDC1?
The strongest Open Targets associations for NPDC1 are neurodegenerative disease, leukocyte count, neutrophil count, myeloid white cell count and monocyte percentage of leukocytes.
How long is the NPDC1 protein?
The Homo sapiens NPDC1 protein (UniProt Q9NQX5) is 325 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NQX5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NQX5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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