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Zinc finger protein 331 (ZNF331)

Homo sapiens — UniProt Q9NQX6

Gene: ZNF331Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Zinc finger protein 331 (ZNF331) is a protein from Homo sapiens identified by UniProt accession Q9NQX6, 463 residues long. MolForge cross-references it against 0 known binders and 130 disease associations.

  • UniProt accession: Q9NQX6; gene symbol ZNF331.
  • Organism: Homo sapiens.
  • Length: 463 amino acids.
  • Top disease associations (Open Targets): cutaneous melanoma, pancreatic ductal adenocarcinoma and breast ductal adenocarcinoma.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameZinc finger protein 331
UniProt accessionQ9NQX6
GeneZNF331
OrganismHomo sapiens
Length463 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (130)

Diseases linked to this target (Open Targets).

  • cutaneous melanoma · score 0.37
  • pancreatic ductal adenocarcinoma · score 0.37
  • breast ductal adenocarcinoma · score 0.37
  • carcinoma of liver and intrahepatic biliary tract · score 0.37
  • bile duct carcinoma · score 0.37
  • lymphoid neoplasm · score 0.37
  • Ovarian Endometrioid Adenocarcinoma with Squamous Differentiation · score 0.37
  • esophageal adenocarcinoma · score 0.37
  • age at menarche · score 0.30
  • IGF-1 measurement · score 0.29

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9NQX6-F1alphafoldPREDICTED76.61—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQX6.

Amino-acid sequence (463 residues)

MAQGLVTFAD VAIDFSQEEW ACLNSAQRDL YWDVMLENYS NLVSLDLESA YENKSLPTEK NIHEIRASKR NSDRRSKSLG RNWICEGTLE RPQRSRGRYV NQMIINYVKR PATREGTPPR THQRHHKENS FECKDCGKAF SRGYQLSQHQ KIHTGEKPYE CKECKKAFRW GNQLTQHQKI HTGEKPYECK DCGKAFRWGS SLVIHKRIHT GEKPYECKDC GKAFRRGDEL TQHQRFHTGE KDYECKDCGK TFSRVYKLIQ HKRIHSGEKP YECKDCGKAF ICGSSLIQHK RIHTGEKPYE CQECGKAFTR VNYLTQHQKI HTGEKPHECK ECGKAFRWGS SLVKHERIHT GEKPYKCTEC GKAFNCGYHL TQHERIHTGE TPYKCKECGK AFIYGSSLVK HERIHTGVKP YGCTECGKSF SHGHQLTQHQ KTHSGAKSYE CKECGKACNH LNHLREHQRI HNS

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with ZNF331?

The strongest Open Targets associations for ZNF331 are cutaneous melanoma, pancreatic ductal adenocarcinoma, breast ductal adenocarcinoma, carcinoma of liver and intrahepatic biliary tract and bile duct carcinoma.

How long is the ZNF331 protein?

The Homo sapiens ZNF331 protein (UniProt Q9NQX6) is 463 amino acids long.

Browse: Targets: Z · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9NQX6
GeneZNF331
OrganismHomo sapiens
Length463
Binders0
Diseases130
View on UniProt