Integral membrane protein 2C (ITM2C)
Homo sapiens — UniProt Q9NQX7
Data last refreshed: (UniProt release unknown)
Key facts
Integral membrane protein 2C (ITM2C) is a protein from Homo sapiens identified by UniProt accession Q9NQX7, 267 residues long. MolForge cross-references it against 0 known binders and 80 disease associations.
- UniProt accession: Q9NQX7; gene symbol ITM2C.
- Organism: Homo sapiens.
- Length: 267 amino acids.
- Top disease associations (Open Targets): mean corpuscular volume, mean corpuscular hemoglobin and mean corpuscular hemoglobin concentration.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Integral membrane protein 2C |
|---|---|
| UniProt accession | Q9NQX7 |
| Gene | ITM2C |
| Organism | Homo sapiens |
| Length | 267 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (80)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.45
- mean corpuscular hemoglobin · score 0.43
- mean corpuscular hemoglobin concentration · score 0.38
- erythrocyte count · score 0.29
- mean reticulocyte volume · score 0.22
- red blood cell density measurement · score 0.15
- Gollop-Wolfgang complex · score 0.05
- tibia, hypoplasia or aplasia of, with polydactyly · score 0.05
- Blount disease · score 0.05
- acheiropody · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NQX7-F1 | alphafold | PREDICTED | 76.18 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQX7.
Amino-acid sequence (267 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ITM2C?
The strongest Open Targets associations for ITM2C are mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, erythrocyte count and mean reticulocyte volume.
How long is the ITM2C protein?
The Homo sapiens ITM2C protein (UniProt Q9NQX7) is 267 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NQX7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NQX7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.