Bridging integrator 3 (BIN3)
Homo sapiens — UniProt Q9NQY0
Data last refreshed: (UniProt release unknown)
Key facts
Bridging integrator 3 (BIN3) is a protein from Homo sapiens identified by UniProt accession Q9NQY0, 253 residues long. MolForge cross-references it against 0 known binders and 111 disease associations.
- UniProt accession: Q9NQY0; gene symbol BIN3.
- Organism: Homo sapiens.
- Length: 253 amino acids.
- Top disease associations (Open Targets): heel bone mineral density, creatinine measurement and vital capacity.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Bridging integrator 3 |
|---|---|
| UniProt accession | Q9NQY0 |
| Gene | BIN3 |
| Organism | Homo sapiens |
| Length | 253 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (111)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.24
- creatinine measurement · score 0.21
- vital capacity · score 0.19
- total blood protein measurement · score 0.18
- FEV/FVC ratio · score 0.17
- glomerular filtration rate · score 0.17
- Parkinson disease · score 0.16
- blood protein measurement · score 0.12
- age at onset · score 0.11
- Myopia · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NQY0-F1 | alphafold | PREDICTED | 92.75 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQY0.
Amino-acid sequence (253 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BIN3?
The strongest Open Targets associations for BIN3 are heel bone mineral density, creatinine measurement, vital capacity, total blood protein measurement and FEV/FVC ratio.
How long is the BIN3 protein?
The Homo sapiens BIN3 protein (UniProt Q9NQY0) is 253 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NQY0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NQY0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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