Ectonucleoside triphosphate diphosphohydrolase 7 (ENTPD7)
Homo sapiens — UniProt Q9NQZ7
Data last refreshed: (UniProt release unknown)
Key facts
Ectonucleoside triphosphate diphosphohydrolase 7 (ENTPD7) is a protein from Homo sapiens identified by UniProt accession Q9NQZ7, 604 residues long. MolForge cross-references it against 0 known binders and 64 disease associations.
- UniProt accession: Q9NQZ7; gene symbol ENTPD7.
- Organism: Homo sapiens.
- Length: 604 amino acids.
- Top disease associations (Open Targets): colorectal cancer, mean corpuscular volume and Leigh syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ectonucleoside triphosphate diphosphohydrolase 7 |
|---|---|
| UniProt accession | Q9NQZ7 |
| Gene | ENTPD7 |
| Organism | Homo sapiens |
| Length | 604 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (64)
Diseases linked to this target (Open Targets).
- colorectal cancer · score 0.27
- mean corpuscular volume · score 0.22
- Leigh syndrome · score 0.19
- platelet crit · score 0.19
- cholestasis, intrahepatic, of pregnancy 3 · score 0.18
- diverticulitis · score 0.17
- leigh syndrome due to mitochondrial complex iv deficiency · score 0.16
- mitochondrial complex IV deficiency, nuclear type 22 · score 0.16
- neurodegenerative disease · score 0.16
- diverticular disease · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NQZ7-F1 | alphafold | PREDICTED | 84.58 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQZ7.
Amino-acid sequence (604 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ENTPD7?
The strongest Open Targets associations for ENTPD7 are colorectal cancer, mean corpuscular volume, Leigh syndrome, platelet crit and cholestasis, intrahepatic, of pregnancy 3.
How long is the ENTPD7 protein?
The Homo sapiens ENTPD7 protein (UniProt Q9NQZ7) is 604 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NQZ7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NQZ7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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