Endothelial zinc finger protein induced by tumor necrosis factor alpha (ZNF71)
Homo sapiens — UniProt Q9NQZ8
Data last refreshed: (UniProt release unknown)
Key facts
Endothelial zinc finger protein induced by tumor necrosis factor alpha (ZNF71) is a protein from Homo sapiens identified by UniProt accession Q9NQZ8, 489 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.
- UniProt accession: Q9NQZ8; gene symbol ZNF71.
- Organism: Homo sapiens.
- Length: 489 amino acids.
- Top disease associations (Open Targets): visual perception measurement, PHF-tau measurement and lymphocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Endothelial zinc finger protein induced by tumor necrosis factor alpha |
|---|---|
| UniProt accession | Q9NQZ8 |
| Gene | ZNF71 |
| Organism | Homo sapiens |
| Length | 489 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (19)
Diseases linked to this target (Open Targets).
- visual perception measurement · score 0.28
- PHF-tau measurement · score 0.25
- lymphocyte count · score 0.12
- non-small cell lung carcinoma · score 0.10
- neoplasm · score 0.10
- alkaline phosphatase measurement · score 0.08
- laryngeal squamous cell carcinoma · score 0.07
- lung adenocarcinoma · score 0.07
- apolipoprotein B measurement · score 0.06
- oral squamous cell carcinoma · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NQZ8-F1 | alphafold | PREDICTED | 76.43 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NQZ8.
Amino-acid sequence (489 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF71?
The strongest Open Targets associations for ZNF71 are visual perception measurement, PHF-tau measurement, lymphocyte count, non-small cell lung carcinoma and neoplasm.
How long is the ZNF71 protein?
The Homo sapiens ZNF71 protein (UniProt Q9NQZ8) is 489 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NQZ8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NQZ8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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