PDZ and LIM domain protein 7 (PDLIM7)
Homo sapiens — UniProt Q9NR12
Data last refreshed: (UniProt release unknown)
Key facts
PDZ and LIM domain protein 7 (PDLIM7) is a protein from Homo sapiens identified by UniProt accession Q9NR12, 457 residues long. MolForge cross-references it against 0 known binders and 430 disease associations.
- UniProt accession: Q9NR12; gene symbol PDLIM7.
- Organism: Homo sapiens.
- Length: 457 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, breast adenocarcinoma and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | PDZ and LIM domain protein 7 |
|---|---|
| UniProt accession | Q9NR12 |
| Gene | PDLIM7 |
| Organism | Homo sapiens |
| Length | 457 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (430)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.46
- breast adenocarcinoma · score 0.18
- neoplasm · score 0.12
- forced expiratory volume · score 0.10
- extranodal nasal NK/T cell lymphoma · score 0.08
- Hodgkins lymphoma · score 0.08
- nonpapillary renal cell carcinoma · score 0.08
- infect · score 0.08
- infection · score 0.08
- lymphoma · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NR12-F1 | alphafold | PREDICTED | 70.27 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NR12.
Amino-acid sequence (457 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PDLIM7?
The strongest Open Targets associations for PDLIM7 are neurodegenerative disease, breast adenocarcinoma, neoplasm, forced expiratory volume and extranodal nasal NK/T cell lymphoma.
How long is the PDLIM7 protein?
The Homo sapiens PDLIM7 protein (UniProt Q9NR12) is 457 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NR12 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NR12 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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