Scavenger receptor cysteine-rich type 1 protein M160 (CD163L1)

Homo sapiens — UniProt Q9NR16

Gene: CD163L1Homo sapiensSwissProt reviewed

Data last refreshed: 2026-04-18 (UniProt release unknown)

Key facts

Scavenger receptor cysteine-rich type 1 protein M160 (CD163L1) is a protein from Homo sapiens identified by UniProt accession Q9NR16, 1453 residues long. MolForge cross-references it against 0 known binders and 37 disease associations.

UniProt accession: Q9NR16; gene symbol CD163L1.
Organism: Homo sapiens.
Length: 1453 amino acids.
Top disease associations (Open Targets): blood protein measurement, L lactate dehydrogenase measurement and creatine kinase measurement.
3D structure: AlphaFold model available.

Target properties

Protein name	Scavenger receptor cysteine-rich type 1 protein M160
UniProt accession	Q9NR16
Gene	CD163L1
Organism	Homo sapiens
Length	1453 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (37)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.45
L lactate dehydrogenase measurement · score 0.42
creatine kinase measurement · score 0.39
body height · score 0.37
adolescent idiopathic scoliosis · score 0.29
low density lipoprotein cholesterol measurement · score 0.22
serum albumin measurement · score 0.12
sex hormone-binding globulin measurement · score 0.11
apolipoprotein A 1 measurement · score 0.09
high density lipoprotein cholesterol measurement · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NR16-F1	alphafold	PREDICTED	72.94	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NR16.

Amino-acid sequence (1453 residues)

MMLPQNSWHI DFGRCCCHQN LFSAVVTCIL LLNSCFLISS FNGTDLELRL VNGDGPCSGT VEVKFQGQWG TVCDDGWNTT ASTVVCKQLG CPFSFAMFRF GQAVTRHGKI WLDDVSCYGN ESALWECQHR EWGSHNCYHG EDVGVNCYGE ANLGLRLVDG NNSCSGRVEV KFQERWGTIC DDGWNLNTAA VVCRQLGCPS SFISSGVVNS PAVLRPIWLD DILCQGNELA LWNCRHRGWG NHDCSHNEDV TLTCYDSSDL ELRLVGGTNR CMGRVELKIQ GRWGTVCHHK WNNAAADVVC KQLGCGTALH FAGLPHLQSG SDVVWLDGVS CSGNESFLWD CRHSGTVNFD CLHQNDVSVI CSDGADLELR LADGSNNCSG RVEVRIHEQW WTICDQNWKN EQALVVCKQL GCPFSVFGSR RAKPSNEARD IWINSISCTG NESALWDCTY DGKAKRTCFR RSDAGVICSD KADLDLRLVG AHSPCYGRLE VKYQGEWGTV CHDRWSTRNA AVVCKQLGCG KPLHVFGMTY FKEASGPIWL DDVSCIGNES NIWDCEHSGW GKHNCVHRED VIVTCSGDAT WGLRLVGGSN RCSGRLEVYF QGRWGTVCDD GWNSKAAAVV CSQLDCPSSI IGMGLGNAST GYGKIWLDDV SCDGDESDLW SCRNSGWGNN DCSHSEDVGV ICSDASDMEL RLVGGSSRCA GKVEVNVQGA VGILCANGWG MNIAEVVCRQ LECGSAIRVS REPHFTERTL HILMSNSGCT GGEASLWDCI RWEWKQTACH LNMEASLICS AHRQPRLVGA DMPCSGRVEV KHADTWRSVC DSDFSLHAAN VLCRELNCGD AISLSVGDHF GKGNGLTWAE KFQCEGSETH LALCPIVQHP EDTCIHSREV GVVCSRYTDV RLVNGKSQCD GQVEINVLGH WGSLCDTHWD PEDARVLCRQ LSCGTALSTT GGKYIGERSV RVWGHRFHCL GNESLLDNCQ MTVLGAPPCI HGNTVSVICT GSLTQPLFPC LANVSDPYLS AVPEGSALIC LEDKRLRLVD GDSRCAGRVE IYHDGFWGTI CDDGWDLSDA HVVCQKLGCG VAFNATVSAH FGEGSGPIWL DDLNCTGMES HLWQCPSRGW GQHDCRHKED AGVICSEFTA LRLYSETETE SCAGRLEVFY NGTWGSVGRR NITTAIAGIV CRQLGCGENG VVSLAPLSKT GSGFMWVDDI QCPKTHISIW QCLSAPWERR ISSPAEETWI TCEDRIRVRG GDTECSGRVE IWHAGSWGTV CDDSWDLAEA EVVCQQLGCG SALAALRDAS FGQGTGTIWL DDMRCKGNES FLWDCHAKPW GQSDCGHKED AGVRCSGQSL KSLNASSGHL ALILSSIFGL LLLVLFILFL TWCRVQKQKH LPLRVSTRRR GSLEENLFHE METCLKREDP HGTRTSDDTP NHGCEDASDT SLLGVLPASE ATK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with CD163L1?

The strongest Open Targets associations for CD163L1 are blood protein measurement, L lactate dehydrogenase measurement, creatine kinase measurement, body height and adolescent idiopathic scoliosis.

How long is the CD163L1 protein?

The Homo sapiens CD163L1 protein (UniProt Q9NR16) is 1453 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

UniProtKB Q9NR16 — name, gene, function, sequence, keywords (CC BY 4.0)
AlphaFold DB Q9NR16 — predicted 3D structure (CC BY 4.0)
Open Targets Platform — disease associations and tractability (CC0)

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