Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC (MAN1C1)
Homo sapiens — UniProt Q9NR34
Data last refreshed: (UniProt release unknown)
Key facts
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC (MAN1C1) is a protein from Homo sapiens identified by UniProt accession Q9NR34, 630 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.
- UniProt accession: Q9NR34; gene symbol MAN1C1.
- Organism: Homo sapiens.
- Length: 630 amino acids.
- Top disease associations (Open Targets): blood protein measurement, pancreatic adenocarcinoma and nonpapillary renal cell carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC |
|---|---|
| UniProt accession | Q9NR34 |
| Gene | MAN1C1 |
| Organism | Homo sapiens |
| Length | 630 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (44)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.33
- pancreatic adenocarcinoma · score 0.21
- nonpapillary renal cell carcinoma · score 0.07
- hepatocellular carcinoma · score 0.05
- neoplasm · score 0.04
- clear cell renal carcinoma · score 0.03
- bacteriemia · score 0.02
- platelet component distribution width · score 0.02
- large cell medulloblastoma · score 0.01
- papillary renal cell carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NR34-F1 | alphafold | PREDICTED | 82.12 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NR34.
Amino-acid sequence (630 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MAN1C1?
The strongest Open Targets associations for MAN1C1 are blood protein measurement, pancreatic adenocarcinoma, nonpapillary renal cell carcinoma, hepatocellular carcinoma and neoplasm.
How long is the MAN1C1 protein?
The Homo sapiens MAN1C1 protein (UniProt Q9NR34) is 630 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NR34 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NR34 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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