Basic leucine zipper transcriptional factor ATF-like 3 (BATF3)
Homo sapiens — UniProt Q9NR55
Data last refreshed: (UniProt release unknown)
Key facts
Basic leucine zipper transcriptional factor ATF-like 3 (BATF3) is a protein from Homo sapiens identified by UniProt accession Q9NR55, 127 residues long. MolForge cross-references it against 0 known binders and 187 disease associations.
- UniProt accession: Q9NR55; gene symbol BATF3.
- Organism: Homo sapiens.
- Length: 127 amino acids.
- Top disease associations (Open Targets): Eczematoid dermatitis, neurodegenerative disease and asthma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Basic leucine zipper transcriptional factor ATF-like 3 |
|---|---|
| UniProt accession | Q9NR55 |
| Gene | BATF3 |
| Organism | Homo sapiens |
| Length | 127 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (187)
Diseases linked to this target (Open Targets).
- Eczematoid dermatitis · score 0.34
- neurodegenerative disease · score 0.34
- asthma · score 0.33
- lymphocyte percentage of leukocytes · score 0.33
- neutrophil percentage of leukocytes · score 0.29
- seasonal allergic rhinitis · score 0.28
- leprosy · score 0.28
- allergic rhinitis · score 0.26
- multiple sclerosis · score 0.26
- type 1 diabetes mellitus · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NR55-F1 | alphafold | PREDICTED | 81.60 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NR55.
Amino-acid sequence (127 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BATF3?
The strongest Open Targets associations for BATF3 are Eczematoid dermatitis, neurodegenerative disease, asthma, lymphocyte percentage of leukocytes and neutrophil percentage of leukocytes.
How long is the BATF3 protein?
The Homo sapiens BATF3 protein (UniProt Q9NR55) is 127 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NR55 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NR55 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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